University of Liverpool, England invites online Application for number of PhD Positions at various Departments. We are providing a list of Fully Funded PhD Positions available at University of Liverpool, England.
Eligible candidate may Apply as soon as possible.
(01) PhD Position – Fully Funded
PhD position summary/title: Accelerated Inorganic Materials Discovery Driven by Magnetic Resonance
This studentship will explore experimental and computational Nuclear Magnetic Resonance (NMR) spectroscopy approaches to probe the fast oxide ion transport (e.g., self-diffusion coefficients, diffusion pathways, dimensionality of motion) of oxide in inorganic materials aimed at establishing design rules for the discovery of next generation fast conductors. The project will (1) develop automated, programmable approaches to data analysis of the NMR measurables that access motion over several time- and length-scales, (2) exploit statistical modelling frameworks to quickly predict NMR properties with high accuracy, validated by experimental NMR measurements, and (3) harness these approaches to build and accelerate structural and diffusion models (e.g., compositional, positional disorders). Examples of current research effort focusing on NMR for oxide and lithium ion transport, and beyond are given.
Deadline : 30 April 2024
(02) PhD Position – Fully Funded
PhD position summary/title: Accelerating computational materials discovery with diverse toolsets for verification and optimisation
Two PhD studentships (1 chemistry, 1 computer science) are available that will tackle the challenge to develop and implement an automated robot-based workflow that will accelerate the materials discovery process. They build on our recent physical science progress in automated synthesis of extended inorganic solids [5] and computer science progress in the diffraction data analysis required to define discovery [6]. The two students will work closely together with a multidisciplinary supervisory team to develop and integrate the methods and tools towards an automated high-throughput workflow that will revolutionise the discovery of functional inorganic materials.
Deadline : 31 December 2024
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(03) PhD Position – Fully Funded
PhD position summary/title: Accelerating energy landscape exploration through optimisation, approximation and parallelisation
Many heuristic methods (random walks, probabilistic selection, genetic algorithms) for energy landscape exploration in Crystal Structure Prediction (CSP) [1] are very important material discovery tools [2]. However, the future of CSP lies in efficient search methods with an explainable outcome and a mathematical guarantee [1,3].
The proposed project will bring new algorithmic approaches and focus on:
- Improving performance guarantee of heuristic methods
- Design of new unbiased search methods
- Development and implementation of parallel algorithms to speed up the exploration.
Deadline : 30 June 2024
(04) PhD Position – Fully Funded
PhD position summary/title: Advanced Information Storage
Digital information can be stored in different types of devices depending on the use and how frequently the data need to be accessed. In a typical computer, data that are infrequently accessed are stored in hard disk drives (HDDs). These can be magnetic devices with high storage density in which binary numbers (“0” and “1”) are encoded in the polarity (spin “up” and “down”) of a magnetic medium. Magnetic data storage is cheap and non-volatile, meaning the data persists after power to the device is cut off, but the speed of accessing the data is relatively slow because the read/write procedures involve moving mechanical parts. Data being frequently required, on the other hand, needs to be accessed on a much faster timescale. Memory devices dedicated to this purpose are volatile random-access memories (RAMs) — solid-state electronic devices in which information is electrically stored. The slow non-volatile and fast volatile memories are physically separated in computers (known as von Neumann architecture), resulting in significant latency as the fast processors must wait for the slow data fetching. This has become the key performance bottleneck for the artificial intelligence (AI) related workloads.
Deadline : 31 July 2024
(05) PhD Position – Fully Funded
PhD position summary/title: Alterations in reparative dentinogenesis with ageing, gender and genetic predisposition
Dental pulp exposure caused by tooth decay or injury can lead to life-threatening infections. Following injury, reparative dentinogenesis serves a vital purpose through the accelerated generation of tertiary dentine, comprising mineral and type I collagen. The regenerative activity is driven by odontoblasts derived from progenitor cells residing in the dental pulp. The effectiveness of regeneration is therefore critical to the dental pulp’s ability to respond to minor tooth injuries such as early tooth decay. At present, this natural defence mechanism can be overwhelmed by rapidly progressing dental decay, which often results in toothache or pulp necrosis. It is therefore critical to understand the mechanism of this intrinsic repair process including the response of the dental pulp to dental cements used during endodontic procedures. At present, there is great reliance upon calcium silicate cements, which have reported positive clinical outcomes in humans, but these fillers fail to fully restore the mineral volume of the affected tooth. To advance the augmentation of natural dentin formation, novel approaches need to be explored, tested, and translated into clinical settings.
Deadline : 1 March 2025
(06) PhD Position – Fully Funded
PhD position summary/title: An investigation of the neural basis of changes in tactile acuity during healthy ageing and its impact on emotional wellbeing
The sense of touch refers to the perception of tactile stimuli through specialised receptors called mechanoreceptors. During tactile exploration, humans typically use their hands, which are densely innervated by these mechanoreceptors. These receptors transduce incoming tactile information, resulting in high sensory acuity. However, as humans age their tactile acuity decreases, which is linked to changes in the peripheral nervous system. Despite this, tactile perception through active exploration (when we use motor control to touch our environment) declines at a slower rate than observed with passive stimulation (when the mechanoreceptors are activated by stroking in absence of movement). Therefore suggesting that tactile acuity during active touch may be supported by additional, or compensatory, central neural mechanisms.
Deadline : 7 June 2024
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(07) PhD Position – Fully Funded
PhD position summary/title: Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity
Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Methotrexate (MTX) is a chemotherapy and immunosuppressive drug, used at a high dose to treat leukaemia, breast cancer, lung cancer and at a lower dose to manage a variety of autoimmune diseases. The most common adverse effects include hepatotoxicity and blood abnormalities with the mechanism of MTX-induced hepatotoxicity obscure. Our preliminary data from a rat model of MTX injury has shown that MTX can adversely affect liver endothelial cell physiology.
Deadline : 29 November 2024
(08) PhD Position – Fully Funded
PhD position summary/title: Antifouling membranes for sustainable water purification and desalination
The EPSRC Centre for Doctoral Training in Net Zero Maritime Energy solutions (N0MES) has a 4-year funded PhD place available for an exceptional researcher. With the support of the University of Liverpool (UoL), Liverpool John Moores University (LJMU) and 33 maritime energy sector partners, N0MES PGRs will pursue new, engineering-centred, interdisciplinary research to address four vital net zero challenges currently facing the North West, the UK and beyond:
a) Energy generation using maritime-based renewable energy (e.g. offshore wind, tidal, wave, floating solar, hydrogen, CCS);
b) Distributing energy from offshore to onshore, including port- and hinterland-side impacts and opportunities;
c) Addressing the short- and long-term environmental impacts of offshore and maritime
environment renewable energy generation, distribution and storage; and
d) Decommissioning and lifetime extension of existing energy and facilities.
Deadline : Open until filled
(09) PhD Position – Fully Funded
PhD position summary/title: Assessing how climate change will impact Cumbrian Coastal Lines (low value of service, but strategically important routes), with a focus on critical infrastructure for freight and energy material transport
The Cumbrian coastal rail-line is a critical infrastructure for local communities and the movement of materials, products and waste within the energy sector. The route is however exposed along several sections to the threat of climate change (sea level rise, changes in storminess, erosion, landslides, heat and flooding).
The studentship would assess the risks and threats posed to Network Rails Cumbrian coastal line assets, from current and future climate change.
- Hazard and risk mapping of the most significant threats to determine the sites at greatest risk from current and future climate change impacts (increased storminess, heat, sea level and fluvial/pluvial flooding), including compound hazard risk.
- Undertake a detailed assessment of critical infrastructure identified at stage 1 to determine future opportunities, management and adaptation plans.
- Providing a toolkit for future adaptation to develop climate resilient futures for different critical infrastructure.
Deadline : 20 May 2024
(10) PhD Position – Fully Funded
PhD position summary/title: Assessing the consistency assumption underlying network meta-analysis in systematic reviews
The assumption of consistency of direct and indirect evidence underlies NMA. The assumption is satisfied when treatment effects estimated by direct evidence agree with those from indirect evidence. For instance, direct evidence for the treatment effect of treatment B versus treatment A is from trials that allocate both treatments A and B, and indirect evidence could be from trials of A vs treatment C and trials of B vs C. If the consistency assumption is violated, NMA results may be unreliable; however, little is known about when results become unreliable and the extent of the unreliability. Various methods exist to assess the consistency assumption, but these methods are considered to have low power to detect inconsistency, and there is no single well- established method. Further, most methods can only be applied when both direct and indirect evidence exist for the same treatment comparison. Where both direct and indirect evidence does not exist, NMA results are often used inappropriately to draw clinical conclusions.
Deadline : 1 October 2024
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(11) PhD Position – Fully Funded
PhD position summary/title: Asset-scale nowcasting of the impact of scour on coastal electricity transmission infrastructure
Coastal electricity transmission infrastructure, such as substations and towers, are a key component of the existing energy network, transmitting high voltage electricity across the country to consumers. The installation of this infrastructure is a key part of future investment in offshore renewable energy, supporting the UK’s ambitious targets to increase offshore wind fivefold to 50GW, and deliver 18GW of electricity interconnector capacity – up from 8.4 GW today – by 2030. National Grid own 21,990 steel lattice towers that support 14,000 km of overhead power lines in England and Wales. They inspect the condition of around 3,650 steel lattice towers each year, and invested £5.4 billion in their distribution network in 2019/20. Scour around tower footings and substation foundations, causing subsistence and possible collapse, is a major risk to this network. However a lack of on-site monitoring poses enormous challenges to focussing maintenance and protection towards the most vulnerable infrastructure.
Deadline : 20 May 2024
(12) PhD Position – Fully Funded
PhD position summary/title: Automated experimental functional materials discovery for net zero technologies
This project, suited to a student with a Physical Sciences or Engineering background, will develop and implement a robot-based materials synthesis workflow that uses a suite of software tools to assist in the key decisions that an experimentalist must make to discover a new functional material. The student will acquire expertise in robotic synthesis platforms, materials synthesis and characterisation and in programming and software organisation, benefitting from the combined physical and computer science supervision. Their project will impact inorganic materials discovery in the most general way imaginable, for example building on our new family of electrolytes for solid state batteries [3].
Deadline : 30 June 2024
(13) PhD Position – Fully Funded
PhD position summary/title: Automated Powder Coating Platform for Long-Life Lithium-ion Batteries
An inorganic synthesis route for coating formation on Li-ion positive electrode powders, utilises a “Sol-Gel” synthetic procedure to form a nanoscale metal-oxide film. The synthesis of inorganic coatings comprises 5 primary steps: solid powder dosing, liquid component dosing, reaction heating/mixing, solvent evaporation/removal, and calcination. The PhD project goal is to combine these existing, and discrete, elements into a fully automated system using a robotic arm. The student will be trained at the interface between the physical and computer sciences to drive implementation of digital and automated methods in (electro)chemistry and frontier battery materials research.
Deadline : 30 June 2024
(14) PhD Position – Fully Funded
PhD position summary/title: Beam gas curtain monitor for the High Luminosity LHC
This PhD project will combine numerical studies using available commercial tools, as well as purpose-developed fluid dynamics and Monte Carlo tools to study the gas jet dynamics in various configurations. In addition, machine learning will be applied to optimize data analysis. All results will be benchmarked against data which the student will obtain from measurements using the existing setup at CERN’s Electron Beam Test Stand (EBTS). Furthermore, the integration of the beam monitor into the wider accelerator control system offers exciting prospects for the development of virtual diagnostics that help optimize experimental output.
Deadline : 30 April 2024
(15) PhD Position – Fully Funded
PhD position summary/title: Biological pathways supporting the formation and function of chromatin (Scholarship)
Every cell in our body contains the same DNA yet each cell expresses a different set of genes. These changes in gene expression are heavily influenced by histone proteins, their role in packaging DNA into chromatin and the “epigenetic” information they carry. Thus, the supply and deposition of histones on chromatin has a profound effect on cell biology and tissue formation. We are interested to understand how histone supply chains change in different cell types including how they are misregulated in cancer.
Deadline : 8 February 2025
(16) PhD Position – Fully Funded
PhD position summary/title: Cardiac Harmony: Modelling Heart Beats with Stem Cells and Code
Despite significant advancements in cardiac research, heart disease remains a leading cause of mortality globally. Unexpected cardiac events can occur even in young, fit individuals engaged in routine activities. One promising avenue of research involves the use of induced pluripotent stem cells (iPSCs) to produce differentiated cardiac cells to replace damaged heart tissue. However, there are still many unknowns regarding the behaviour and connectivity of these cells in vitro.
This project aims to culture cardiac myocytes from iPSCs and develop computer models to simulate their activity and interconnections. The ultimate goal is to use the in silico model to elucidate the limitations of the in vitro stem cell model and identify specific pathways to improvement.
Deadline : 1 March 2025
(17) PhD Position – Fully Funded
PhD position summary/title: Cardiovascular and Neuromuscular Functions around the Clock: Harnessing Protective Endogenous Mechanisms towards Smarter Design of Novel Therapies and Interventions
This exciting PhD project will test the main hypothesis that disruption of circadian clocks within the cardiovascular system leads to disrupted molecular pathway within the cardiovascular system and that realigning circadian clocks is essential for designing effective therapies for improving cardiovascular health. We will investigate the following three major aims:
- Identify the key biomarkers regulated by the circadian cardiovascular or neuromuscular systems, and how they change with age.
- Evaluate how the circadian pathway regulation is changed in preclinical models of heart failure and physiological hypertrophy or sarcopenia and diabetic neuropathy (muscle wasting).
- Test the optimal time-of-day pharmacological and time-of-day light/diet/exercise regimes in their ability to boost circadian metabolism within the cardiovascular or neuromuscular system.
Deadline : 1 March 2025
About The University of Liverpool, England : Official Website
The University of Liverpool (abbreviated UOL) is a public research university in Liverpool, England. Founded as a college in 1881, it gained its Royal Charter in 1903 with the ability to award degrees, and is also known to be one of the six ‘red brick’ civic universities, the first to be referred to as The Original Red Brick. It comprises three faculties organised into 35 departments and schools. It is a founding member of the Russell Group, the N8 Group for research collaboration and the university management school is triple crown accredited.
Ten Nobel Prize winners are amongst its alumni and past faculty and the university offers more than 230 first degree courses across 103 subjects. Its alumni include the CEOs of GlobalFoundries, ARM Holdings, Tesco, Motorola and The Coca-Cola Company. It was the UK’s first university to establish departments in oceanography, civic design, architecture, and biochemistry (at the Johnston Laboratories). In 2006 the university became the first in the UK to establish an independent university in China, Xi’an Jiaotong-Liverpool University, making it the world’s first Sino-British university. For 2022–23, Liverpool had a turnover of £673.2 million, including £118 million from research grants and contracts. It has the seventh-largest endowment of any university in England. Graduates of the university are styled with the post-nominal letters Lpool, to indicate the institution.
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